Eschaton 2012 - Ania Bula: —phobias and —isms
Ania Bula is an English, biology, and psychology student at the University of Ottawa with an interest in sexology. She is the founder of the It’s Not Your Fault Project, an online support group for victims of sexual assault.
She is a tireless activist for feminism, skepticism, LGBTQ rights, atheism, and other social justice issues, which she explores both in her blog (co-written with Alexander Gonzalez) and in fantasy writing.
Sound effect by HerbertBoland http://www.freesound.org/people/HerbertBoland/sounds/33637/
Conference by CFI Ottawa filmed with permission
Outdoor air pollution has been definitively linked to cancer and is officially classified as a carcinogen, according to research released Thursday by The International Agency for Research on Cancer (IARC), part of the World Health Organization.
“The air we breathe has become polluted with a mixture of cancer-causing substances,” said Kurt Straif, head of the IARC’s monographs section, which is tasked with ranking carcinogens.
The IARC’s research found the toll of air pollution on public health worldwide is significant. In 2010 alone, exposure to ambient fine particles was recently estimated to have contributed to 3.2 million premature deaths, predominantly from cardiovascular disease, and 223,000 deaths from lung cancer. More than half of the lung cancer deaths attributable to ambient fine particles were projected to have been in China and other East Asian countries.
Sources of air pollution identified by the agency include emissions from motor vehicles, industrial processes, power plants and household heating and cooking fumes and while the chemical makeup of outdoor air pollution varies around the globe, the IARC was clear that “the mixtures of ambient air pollution invariably contain specific chemicals known to be carcinogenic to humans.”
Higher levels of air pollution have long been connected to an array of health problems, such as increased rates of asthma and heart disease, and millions of deaths annually around the world. In making the case for the Obama administration’s new standards aimed at limiting the amount of carbon pollution emitted by coal-fired power plans, Environmental Protection Agency head Gina McCarthy noted that “the nation’s asthma rates have already doubled over the past 30 years.”
But the WHO’s link between air pollution and cancer is a significant revelation that underscores the urgency of reducing pollution levels worldwide. The expert panel analyzed more than 1,000 studies worldwide and found enough evidence to conclude exposure to outdoor air pollution causes lung cancer. “Our task was to evaluate the air everyone breathes rather than focus on specific air pollutants,” said Dana Loomis, deputy head of the monographs section. “The results from the reviewed studies point in the same direction: the risk of developing lung cancer is significantly increased in people exposed to air pollution.” The agency also linked air pollution to increased risk of bladder cancer.
“This is something governments and environmental agencies need to take care of,” Straif emphasized. “People can certainly contribute by doing things like not driving a big diesel car, but this needs much wider policies by national and international authorities.”
The chemical prevented all brain cell death in mice when confronted with prion disease. While this is a long way from preventing Alzheimer’s in humans, it is the first time that an animal has been able to stave off neurodegeneration. More info: http://bbc.in/1gu3sek Photo via: Obscenity 10th Oct episode of the new IFLS show now live! Watch it here: http://bit.ly/15XDuOu
This week in science.
New form of matter: http://bit.ly/18CYkz3
Climate change: http://bbc.in/19P6vax
Jaw & backbone: http://bit.ly/15Dv3HJ
Solar panels: http://bit.ly/167lCyT
It was an amazing victory for mental health treatment reform activists and one investigative reporter: on Aug. 28, 2013, National Institute of Mental Health director Thomas Insel announced that psychiatry’s standard treatment for people diagnosed with schizophrenia and other psychoses needs to change.
After examining two long-term studies on schizophrenia and psychoses, Insel came to what was previously considered a radical conclusion: in the long-term, some individuals with a history of psychosis do better off medication.
Insel finally recognized what mental health treatment reform activists and investigative reporter Robert Whitaker have been talking about for years—the research shows that American psychiatry’s standard treatment protocol has hurt many people who could have been helped by a more selective and limited use of drugs, and a more diverse approach such as the one used in Finland, which has produced the best long-term outcomes in the developed world.
Like many treatment reform activists and Whitaker, Insel does not completely reject the use of medications, but instead called for a more judicious use of them. Insel concluded:
Antipsychotic medication, which seemed so important in the early phase of psychosis, appeared to worsen prospects for recovery over the long-term….
It appears that what we currently call “schizophrenia” may comprise disorders with quite different trajectories. For some people, remaining on medication long-term might impede a full return to wellness. For others, discontinuing medication can be disastrous.
What is amazing about this recent conclusion by the NIMH director is that it means less money for drug companies, which in the past, have heavily influenced psychiatric treatment through their financial clout. Big Pharma has profited enormously from the current standard treatment protocol that calls for lifetime antipsychotic medication after a single psychotic episode. Because of this treatment protocol and the increasing use of antipsychotic drugs for nonpsychotic conditions, antipsychotics grossed over $18 billion a year in the United States by 2011. The antipsychotic Abilify became the highest grossing of all drugs in the first quarter of 2013, and it is on track to gross $6 billion this year (entire corporations that only grossed approximately $5 billion last year include Facebook and Yahoo).
How Did This Activist Victory Happen?
For several decades, a small group of mental health treatment reform activists, comprised of dissident mental health professionals and “psychiatric survivors” (who themselves had received nonproductive and counterproductive treatments) have been engaged in an uphill battle for truly informed choice, including multiple options which reflect the diversity of the population diagnosed with schizophrenia and other psychoses.
Dissident psychologists, psychiatrists and other mental health professionals at the International Society for Ethical Psychology and Psychiatry, patient and ex-patient activists at MindFreedom International, and patients’ rights advocates at National Association for Rights, Protection and Advocacy have not received attention from the mental health establishment or from most of the mainstream media. But they aroused the curiosity of investigative reporter Robert Whitaker.
In 1998, Whitaker co-wrote a series on psychiatric research for the Boston Globe that was a finalist for the Pulitzer Prize for Public Service. The more Whitaker dug, the more he uncovered glaring problems in standard psychiatric treatment. He found a dramatic rise in U.S. mental illness disability rates; research revealing the failure of standard psychiatric treatment protocols; World Health Organization findings that schizophrenia outcomes are much better in India and Nigeria than in the United States; WHO findings of an association between good outcomes and not remaining continuously on psychiatric drugs; and treatment options that were far more effective than American psychiatry’s standard of care. His book Mad in America: Bad Science, Bad Medicine, and the Enduring Mistreatment of the Mentally Ill was published in 2001.
Whitaker did not let go of this story until the mental health establishment was forced to listen. In 2010, Whitaker’s book Anatomy of an Epidemic: Magic Bullets, Psychiatric Drugs, and the Astonishing Rise of Mental Illness in America won the Investigative Reporters and Editors book award for best investigative journalism. The mental health establishment could no longer ignore him, and so they invited Whitaker to their institutions to speak with the hopes of discrediting him, but they could not do so.
The Research That Convinced the NIMH Director
One of the two major research studies NIMH director Insel adduced to justify his recent conclusions is a study on long-term treatment of schizophrenia by Martin Harrow, a psychologist at the University of Illinois Medical School. Ironically, Harrow’s study had been rescued from oblivion by Whitaker in Anatomy of an Epidemic,after NIMH and the mental health establishment had buried it. As Whitaker noted:
In 2007, the year [Harrow] published his [15-year] results in the Journal of Nervous and Mental Disease, NIMH issued 89 press releases, many on inconsequential matters. But it did not issue one on Harrow’s findings, even though his was arguably the best study of the long-term outcomes of schizophrenia patients that had ever been done in the United States.
What is so important about the Harrow study for Whitaker—and now for Insel? In February 2012, Harrow published his 20-year followup, “Do All Schizophrenia Patients Need Antipsychotic Treatment Continuously Throughout their Lifetime? A 20-Year Longitudinal Study, which reiterated his 2007 conclusions. Specifically, Harrow found that patients diagnosed with schizophrenia who were “not on antipsychotics for prolonged periods were significantly less likely to be psychotic and experienced more periods of recovery.”
Harrow and his research team had enrolled patients from two Chicago hospitals diagnosed with schizophrenia (as well as patients diagnosed with mood disorders with psychosis) to examine long-term outcomes. All of the patients had received conventional medication treatments when hospitalized, and then Harrow followed them as their lives unfolded, periodically assessing how well they were doing. The majority of patients continued their antipsychotic medications, while about a third of them did not comply with medication treatment and stopped taking them.
The 20-year results, like the 15-year results, showed that patients diagnosed with schizophrenia (and those patients with mood disorders with psychosis) who took antipsychotic medication regularly during the 20 years actually experienced more psychosis, more anxiety, and were more cognitively impaired and had fewer periods of sustained recovery than those who quit taking antipsychotic medications.
The psychiatric establishment, after first burying the Harrow study, tried to minimize its importance when Whitaker brought it to public attention in Anatomy of an Epidemic. Prior to Insel’s recent acknowledgement of its importance, the psychiatric establishment claimed Harrow’s study proved nothing because it was a prospective, naturalistic study, not a randomized design. But in July 2013, Dutch researcher Lex Wunderink and his team published a study in JAMA Psychiatry which used a randomized design, the “gold standard” of research, and Wunderink had similar results as Harrow. The psychiatric establishment had been checkmated.
Specifically, Wunderink reported on a seven-year follow-up of people diagnosed with schizophrenia and related disorders who had experienced a first episode of psychosis. After six months of remission following antipsychotic treatment, the patients were randomly assigned to either maintenance on antipsychotic drugs or a tapering-off and discontinuation of the drugs. Insel himself summarizes the results: “By seven years, the discontinuation group had achieved twice the functional recovery rate: 40.4 percent vs. only 17.6 percent among the medication maintenance group.”
Accompanying the study by Wunderink, a JAMA Psychiatry editorial argues that psychiatry needs to respond to this data and adopt new drug-use protocol:
In moving to a more personalized or stratified medicine, we first need to identify the very small number of patients who may be able to recover from first episode psychosis with intensive psychosocial interventions alone. For everyone else, we need to determine which medication, for how long, in what minimal dose, and what range of intensive psychosocial interventions will be needed to help them get well, stay well, and lead fulfilling and productive lives. These factors have rarely been the goal in the real world of clinical psychiatry—something we must finally address now that we are armed with stronger evidence to counter poor practice.
Finland’s Open Dialogue: A Better Approach Already Exists
While Insel’s announcement acknowledged both the Harrow and the Wunderink findings that Whitaker had worked hard to make known, Insel omits a proven alternative. Open Dialogue therapy in northern Finland has, for more than two decades, provided the kind of treatment that Harrow’s and Wunderink’s research recommends. Whitaker had detailed Open Dialogue in Anatomy of an Epidemic, and he summarizes it in his July 13, 2013 blog, “Harrow + Wunderink + Open Dialogue = An Evidence-based Mandate for A New Standard of Care.”
The Open Dialogue therapy protocol delays the use of antipsychotics in first-episode patients, instead using psychosocial support and selective use of anxiety-reducing benzodiazepines (e.g. Ativan, Klonopin,Valium) with the hope that patients can “chill out,” and get through their first crisis without ever going on antipsychotic medications. If patients need to go on antipsychotics, the Open Dialogue protocol allows for them to subsequently try to taper from the drugs.
The results? “With this selective use of antipsychotics,” Whitaker reports, “Open Dialogue has produced the best long-term outcomes in the developed world. At the end of five years, 67% of their first-episode patients have never been exposed to antipsychotics, and only 20% are maintained regularly on the drugs. With this drug protocol, 80% of first episode patients do fairly well over the long-term without antipsychotics.”
The Harrow and the Wunderinks studies, Open Dialogue, and the lives of many ex-patient activists dispel the myth that people do not fully recover from psychotic states. The reality is that people can experience long-term recovery, and for many of these people, rejecting standard psychiatric treatment has been their salvation. It is good news for them and the rest of us that the director of NIMH has finally acknowledged this reality.